Eric Karl Richfield, M.D., Ph.D.

   
 

Associate Professor 
Department of Pathology and Laboratory Medicine

UMDNJ-Robert Wood Johnson Medical School
One Robert Wood Johnson Place - MEB 212
New Brunswick, NJ 08901

 




Environmental & Occupational Health Sciences Institute
170 Frelinghuysen Road
Piscataway, NJ 



Clinical Expertise:

Dr. Richfield performs clinical diagnostic neuropathology.  This includes evaluation of brain and spinal cord biopsies and the postmortem examination of brain and spinal cord.  Forensic and legal cases are also evaluated.  


Research Expertise:

The lab is currently studying pathologic changes in Alzheimer’s and Parkinson’s disease using pre- and 
postmortem human tissue.  A variety of tools are used to evaluate clinical grade of disease and pathogenesis including morphological counting and other measurements, immunohistochemistry, and Western blotting. Cerebrospinal fluid and blood are being investigated for use in diagnosis and grading of severity.  


Undergraduate Education:

  • University of Wisconsin-Milwaukee - Milwaukee, WI 
    B.S., Applied Math and Physics, Magna Cum Laude, 09/71-05/75 


Graduate Education:

  • Medical College of Wisconsin - Milwaukee, WI
    Doctor of Medicine, 06/75-05/80   

  • University of Michigan - Ann Arbor, MI
    Doctor of Philosophy, Neurosciences, 06/83-12/87  
    Master of Science, Program in Clinical Research Design and Statistical Analysis, 08/88


Postgraduate Training:

  • St. Joseph's Hospital - Milwaukee, WI 
    Internship, Department of Medicine, 07/80-06/81 

  • University of Michigan - Ann Arbor, MI
    Residency, Department of Neurology, 07/81-06/84 
    Fellowship, Department of Neurology/Specialty Training - Movement Disorders, 07/84-10/87 

  • National Institute of Mental Health - Washington, DC
    Unit of Functional Neuroanatomy, Clinical Neuroendocrinology Branch, 11/87-07/89         

  • University of Rochester School of Medicine and Dentistry - Rochester, NY
    Residency, Department of Pathology, Specialty Training – Neuropathology, 07/95-06/97 


Academic Appointments:

  • UMDNJ-Robert Wood Johnson Medical School - New Brunswick/Piscataway, NJ
    Associate Professor, 07/03 to Present 

  • University of Rochester - Rochester, NY  
    Associate Professor, Department of Pathology, 07/97-06/03
    Associate Professor, Department of Pharmacology and Physiology, 07/95-6/03
    Assistant Professor, Department of Pharmacology and Physiology, 07/91-06/95 
    Assistant Professor, Department of Neurology, 07/89-06/95       


Hospital Appointments:

  • Robert Wood Johnson University Hospital - New Brunswick, NJ
    Staff Pathologist, 07/03 to Present
  • University of Rochester Medical Center - Rochester, NY         
    07/89-08/03
  • Monroe Community Hospital - Rochester, NY
    Chief of Service, Geriatric Neurology Unit, 07/93-06/95   


Licensure:

  • State of Michigan Medical License 
  • State of New York Medical License 
  • State of New Jersey Medical License 


Certification:

  • 1981 - Diplomat, National Board of Medical Examiners
  • 1986 - Diplomat in Neurology, American Board of Psychiatry & Neurology Certificate No. 28202
  • 1997 - Diplomat in Neuropathology, American Board of Pathology


Professional Organizations:

  • Society for Neuroscience
  • American Association of Neuropathologists, Inc. 


Service on UMDNJ Committee:

  • MD - PhD Admissions Committee 

Selected Publications:

  • Nicholas, A, de Magalhaes, J.P., Kraytsberg, Y., Richfield, E.K., Levanon, E.Y., and Khrapko, K. (2010) Age-related gene-specific changes of A-to-I mRNA editing in the human brain.  Mechanisms of Ageing and Development 131: 445-447.
  • Prasad, K. and Richfield, E.K. (2010) Real time epifluorescence stereology and morphology of neurons in the mouse substantia nigra and ventral tegmental area.  Experimental Neurology 225:328-340. 
  • Kavita Prasad, Elizabeth Tarasewicz, Pamela A. Ohman Strickland, Michael O’Neill, Stephen N. Mitchell,  Kalpana Merchant, Samnang Tep, Kathryn Hilton, Akash Datwani, Manuel Buttini, Sarah Mueller-Steiner,  and Eric K. Richfield. (2011) Biochemical and morphological consequences of human a-synuclein expression in a mouse a-synuclein null background. European Journal of Neuroscience European  Journal of Neuroscience 33:642-656. 
  • Yin, L., Lu, L., Prasad, K., Richfield, E.K., Unger, E., Xu, J., and Jones, B.C. (2011) Genetically-Based  Differential Susceptibility to Paraquat Neurotoxicity in Mice Neurotoxicology & Teratology (in press).
  • Peneder, T.M., Berger, M., Scholze, P., Heinze, G., Bertl, J., Bauer, J., Richfield, E.K. Hornykiewicz, O., Pifl C. (2011) Chronic exposure to manganese decreases striatal dopamine turnover in human alpha-synuclein transgenic mice. Neuroscience (in press).
  • Lipoff, D.M., Bhambri, A., Fokas, G., Sharma, S., Gabel, L.A., Brumberg, J.C., Richfield, E.K., Ramos, R.L.  (2011) Neocortical Molecular Layer Heterotopia in Substrains of C57BL/6 and C57BL/10 Mice. Brain  Research  (in press)